Pharmacology

Antifungals

Antifungals

Antifungals, also called antimycotics, are drugs that are used to treat fungal infections. Fungal infections usually attack people with weak immunity. Antifungal drugs include; Pregnancy Category: C They are generally categorized as category C. Animal studies have shown potential risks of antifungals to the fetus. But when they are intravaginally as in cases of nystatin […]

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Fluoroquinolones

Fluoroquinolones

Fluoroquinolones are antibiotic successors of nalidixic acid. They offer greater efficacy, a broader spectrum of activity, and are safer than their predecessors. They include; Ciprofloxacin Gemifloxacin Levofloxacin Moxifloxacin Norfloxacin Ofloxacin Pregnancy Category: C They can be used with caution if the benefits outweigh the risks Mechanism of Action Fluoroquinolones disturb DNA replication in susceptible gram-negative

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Carbapenems

Carbapenems

Carbapenems are broad spectrum antibiotics that are mostly used in cases of severe infections. They are mostly given via injections and are sometimes used concurrently with aminoglycosides since they are synergistic. They include; Meropenem Ertapenem Imipenem-cilastatin Doripenem Imipenem is mostly combined with cilastatin and/or relebactam (non-antibiotics drugs) because they protect it from being broken down.

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